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Chelerythrine 34316-15-9

Chelerythrine 34316-15-9

Chelerythrine HPLC 98% CAS#:34316-15-9 M.F: C21H18NO4 M.W: 348.378g/mol

Detailed description

HC026155-----Chelerythrine 

analytical standard     HPLC 98%


 

Synonym:

Chelerythrine,Toddaline

Cas Number:34316-15-9
Molecular Formula:C21H18NO4
Molecular Weight:348.378g /mol 

 

Chemical Name:

1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium

Appearance:white   powder
Grade:analytical standard
Assay:≥98%(HPLC)
Chemical Family:Alkaloids compounds
Original:Macleaya cordata (Willd.) R. Brown
Storage temp:2~8°C
Pack Size:20mg;100mg;1gram ;10gram;100g;1kg
Application:For laboratory research use only

 



Articles:



1.Chelerythrine Down Regulates Expression Of VEGFA, BCL2 And KRAS By Arresting G-Quadruplex Structures At Their Promoter Regions.

Jana J, Mondal S, Bhattacharjee P, Sengupta P, Roychowdhury T, Saha P, Kundu P, Chatterjee S.

Abstract

A putative anticancer plant alkaloid, Chelerythrine binds to G-quadruplexes at promoters of VEGFA, BCL2 and KRAS genes and down regulates their expression. The association of Chelerythrine to G-quadruplex at the promoters of---Read More.


2.Chelerythrine promotes Ca2+-dependent calpain activation in neuronal cells in a PKC-independent manner.

Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E.

Abstract

BACKGROUND:

Chelerythrine is widely used as a broad range protein kinase C (PKC) inhibitor, but there is controversy about its inhibitory effect. Moreover, it has been shown to exert PKC-independent effects on non-neuronal cells---Read More.


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