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Sennoside A,81-27-6

Sennoside A,81-27-6

Sennoside B HPLC 98% CAS#:81-27-6 M.F: C42H38O20 M.W:862.74g/mol

Detailed description


HS053278-----Sennoside A

analytical standard     HPLC 98%




Synonym:

Sennoside A

Cas Number:81-27-6
Molecular Formula:C42H38O20
Molecular Weight:862.74g/mol



Chemical Name:

(9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

Appearance:white  powder
Grade:analytical standard
Assay:≥98%(HPLC)
Chemical Family:Anthraquinone compounds
Original:Cassia angutifolia Vahl
Storage temp:2~8°C
Pack Size:20mg;100mg;1gram;10gram
Application:For laboratory research use only

 



Articles:



1.Sennoside A, Derived From The Traditional Chinese Medicine Plant Rheum L., Is A New Dual HIV-1 Inhibitor Effective On HIV-1 Replication.

Esposito F, Carli I, Del Vecchio C, Xu L, Corona A, Grandi N, Piano D, Maccioni E, Distinto S, Parolin C, Tramontano E.

Abstract

BACKGROUND:

Despite the availability of effective antiretroviral therapies, drugs for HIV-1 treatment with new mode of action are still needed. An innovative approach is aimed to identify dual HIV-1 inhibitors---Read More.


2.Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis.

Lee SY, Kim W, Lee YG, Kang HJ, Lee SH, Park SY, Min JK, Lee SR, Chung SJ.

Abstract

Phospho-cofilin (p-cofilin), which has a phosphate group on Ser-3, is involved in actin polymerization. Its dephosphorylated form promotes filopodia formation and cell migration by enhancing actin depolymerization---Read More.



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