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Arenobufagin HPLC 98% .Cas# 464-74-4 .M.F: C24H32O6 .M.W : 416.50

Detailed description

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 HA009064 -----Arenobufagin

analytical standard


Cas Number:464-74-4
Molecular Formula:C24H32O6
Molecular Weight:416.50


Chemical Name:12-Oxo-3-beta,11-alpha,14-trihydroxy-5-beta-bufa-20,22-dienolide
Appearance:White powder
Grade:analytical standard
Chemical Family: Bufadienolides compounds
Original:Bufo bufo gargarizans Cantor
Storage temp:2~8°C
Pack Size:20mg; 100mg; 1gram ;10gram
Application:For laboratory research use only



1. Arenobufagin Activates P53 To Trigger Esophageal Squamous Cell Carcinoma Cell Apoptosis In Vitro And In Vivo.

Lv J, Lin S, Peng P, Cai C, Deng J, Wang M, Li X, Lin R, Lin Y, Fang A, Li Q.



Esophageal squamous cell carcinoma (ESCC) is often diagnosed at late incurable stage and lacks effective treatment strategy. Bufadienolides  are cardiotonic steroids isolated from the skin and parotid venom glands of the toad Bufo bufo gargarizans Cantor with novel anticancer activity. However, there is little information about the effects and action mechanisms of---Read More

2.Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells.

Yue Q, Zhen H, Huang M, Zheng X, Feng L, Jiang B, Yang M, Wu W, Liu X, Guo D.



Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough. Toad venom extract containing bufadienolides, which belong to cardiac steroids---Read More



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