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Arenobufagin-464-74-4

Arenobufagin-464-74-4

Arenobufagin HPLC 98% .Cas# 464-74-4 .M.F: C24H32O6 .M.W : 416.50

Detailed description

If you are planning to wholesale arenobufagin from one of the professional China arenobufagin manufacturers and suppliers, please feel free to contact Baoji Herbest Bio-Tech Co.,Ltd.

 HA009064 -----Arenobufagin

analytical standard


 

Synonym:Bufarenogin
Cas Number:464-74-4
Molecular Formula:C24H32O6
Molecular Weight:416.50


 

Chemical Name:12-Oxo-3-beta,11-alpha,14-trihydroxy-5-beta-bufa-20,22-dienolide
Appearance:White powder
Grade:analytical standard
Assay:≥98%(HPLC)
Chemical Family: Bufadienolides compounds
Original:Bufo bufo gargarizans Cantor
Storage temp:2~8°C
Pack Size:20mg; 100mg; 1gram ;10gram
Application:For laboratory research use only

 


 Articles:


1. Arenobufagin Activates P53 To Trigger Esophageal Squamous Cell Carcinoma Cell Apoptosis In Vitro And In Vivo.

Lv J, Lin S, Peng P, Cai C, Deng J, Wang M, Li X, Lin R, Lin Y, Fang A, Li Q.

 PMID:28280360

Abstract

Esophageal squamous cell carcinoma (ESCC) is often diagnosed at late incurable stage and lacks effective treatment strategy. Bufadienolides  are cardiotonic steroids isolated from the skin and parotid venom glands of the toad Bufo bufo gargarizans Cantor with novel anticancer activity. However, there is little information about the effects and action mechanisms of---Read More


2.Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells.

Yue Q, Zhen H, Huang M, Zheng X, Feng L, Jiang B, Yang M, Wu W, Liu X, Guo D.

PMID:
 
27428326

Abstract

Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough. Toad venom extract containing bufadienolides, which belong to cardiac steroids---Read More

 

 

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