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Bufalin-465-21-4

Bufalin-465-21-4

Specification of Bufalin HPLC/MS/NMR

Detailed description

HB009065 -----Bufalin

analytical standard



Synonym:5beta,20(22)-Bufadienolide-3beta,14-diol
Cas Number:465-21-4
Molecular Formula:C24H34O4
Molecular Weight:386.52


Chemical Name:5beta)-3,14-dihydroxybufa-20,22-dienolide
Appearance:White powder
Grade:analytical standard
Assay:≥98%(HPLC)
Chemical Family:Bufadienolides compounds
Original:Bufo bufo gargarizans Cantor
Storage temp:2~8°C
Pack Size:20mg; 100mg; 1gram ;10gram
Application:For laboratory research use only


Item and NamePack SizePrice(USD)Payment
HB009065 --Bufalin20mg216.00PayPal
HB009065 --Bufalin100mg550.00PayPal
HB009065 --Bufalin500mg1135.00PayPal
HB009065 --Bufalin1g1715.00PayPal




Articles:


1.Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1.

Ying Wang, David M Lonard, Yang Yu, Dar-Chone Chow, Timothy G Palzkill, Jin Wang, Ruogu Qi, Alexander J Matzuk, Xianzhou Song, Franck Madoux, Peter Hodder, Peter Chase, Patrick R Griffin, Suoling Zhou, Lan Liao, Jianming Xu, Bert W O'Malley

PMID 24390736

Abstract

Virtually all transcription factors partner with coactivators that recruit chromatin remodeling factors and interact with the basal transcription machinery. Coactivators have been implicated in ...Read More


2. Bufalin enhances anti-angiogenic effect of sorafenib via AKT/VEGF signaling.

Haiyong Wang, Chenyue Zhang, Zhouyu Ning, Litao Xu, Xiaoyan Zhu, Zhiqiang Meng

PMID 26782953

Abstract

Sorafenib mainly exerts its anti-hepatoma effect by inhibiting tumor angiogenesis. However, its curative effect is limited. Thus application of drugs which could augment its anti-angiogenic effect is necessary. Bufalin has...Read More




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