Diosgenin,512-04-9

Diosgenin HPLC 98% CAS#：512-04-9 M.F: C27H42O3 M.W: 414.63

Detailed description

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HD101369-----Diosgenin

analytical standard HPLC 98%‍

Synonym:	Nitogenin
Cas Number:	512-04-9
Molecular Formula:	C27H42O3
Molecular Weight:	414.63

Chemical Name:	(22R,25R)-Spirosta-5-ene-3β-ol
Appearance：	off-white powder
Grade:	analytical standard
Assay:	≥98%(HPLC)
Chemical Family:	saponins compound
Original:	Dioscorea Nipponica
Storage temp：	2~8°C
Pack Size:	20mg;100mg;1gram;10gram
Application：	For laboratory research use only

Articles:

1.Diosgenin Inhibits Angiotensin II-Induced Extracellular Matrix Remodeling In Cardiac Fibroblasts Through Regulating The TGF‑Β1/Smad3 Signaling Pathway.

Zhou HT, Yu XF, Zhou GM.

PMID:

28260007

Abstract

The proliferation of cardiac fibroblasts (CFs) and deposition of extracellular matrix (ECM) proteins are pivotal in the development of cardiac fibrosis. Recent studies have indicated that diosgenin may inhibit---Read More.

2.Effect of orally ingested diosgenin into diet on skin collagen content in a low collagen skin mouse model and its mechanism of action.

Haratake A, Watase D, Setoguchi S, Nagata-Akaho N, Matsunaga K, Takata J.

PMID:

28259652

Abstract

AIMS:

Influence on collagen content with oral ingestion of diosgenin (Dios) was investigated in established low collagen skin mouse model. And its mechanism of action was investigated using primary cultured fibroblasts---Read More.